Vlad Coric , M. There is an urgent unmet need for safe, effective treatments for pain, and TRPM3 antagonism is a promising approach to advance new pain therapies. Based on the extensive characterization of the mechanism and encouraging preclinical data generated to date by KU Leuven, we are excited to collaborate with these academic leaders to bring BHV into clinical development. Their research provides a strong rationale for advancing TRPM3 modulators to treat pathological pain.
I'm excited to carry BHV forward as the first candidate in a potentially transformative class of pain therapies. The portfolio includes the lead candidate, henceforth known as BHV, which has demonstrated promising efficacy in preclinical pain models and will be the first to advance towards Phase 1 studies.
KU Leuven will receive an upfront payment and is eligible to receive additional development, regulatory, and commercialization milestones. In addition, KU Leuven will be eligible to receive mid-single digit royalties on net sales of products resulting from the collaboration. Biohaven has a proven track record of successfully developing and launching novel therapies, and we're excited to work with Biohaven through this global license and research collaboration agreement. More information about Biohaven is available at www.
About KU Leuven, CD3 and LICR As the number one European university for innovation, KU Leuven actively invests in launching innovative technologies in the commercial market by creating spin-off companies, securing and licensing intellectual property, and collaborating with industry.
KU Leuven supports researchers and students in transforming their innovative ideas and technologies into commercial products and services that impact people's lives across the globe. Ever since , LRD has been building bridges between science and industry. For more information, please visit: lrd. The Centre for Drug Design and Discovery CD3 translates innovative science into promising drug discovery programs that are well qualified for further development by pharmaceutical or biotech companies.
CD3 brings expert drug discovery capabilities and financial means to academic research groups and small companies in order to discover innovative drugs.
For more information, please visit www. The Laboratory of Ion Channel Research LICR studies ion channels in all their facets, from their molecular and cellular mode of action to their role in health and disease. The central focus is on Transient Receptor Potential TRP channels, a superfamily of cation channels involved in a wide array of physiological processes, including sensory processing and pain signaling.
Through intense collaboration with clinical researchers and medicinal chemists, LICR aims at translating fundamental insights on TRP channel biology towards new therapies. Download Durchstarten - Deutsch - Bisherige Ausgabe: 5. Schulstufe: 1. Standard-Tests pdf Mag. Ewald Cerwenka. Download Gesammelte Werke.
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